G e n e t i c s   &   R e p r o d u c t i o n :     L e c t u r e  # 16 Vocabulary | Study Questions
Human Reproduction
Objectives:
  1. Understand the structures and functions of the male and female reproductive systems.
  2. Understand the hormone interactions associated with sexual maturation and reproduction.
  3. Become aware of the LDS policy on contraception and how it relates to individual members.
  1. Human reproduction
    Very relevant to our situation.
    1. Four crucial points
      The process of meiosis (the formation of gametes: sex cells) is the generally the same for all organims: fish, chickens, plants. But, specifically, there are crucial differences:
      1. Internal fertilization
        Fertilization occurs within the female. (Fish: external reproduction: eggs are desposited in the water, onto which males excrete sperm.)
      2. Human sexual behavior conforms to fundamental principles of reproductive biology
        Sexual reproduction.
      3. Gonads are gamete producing structures
        1. Ovaries in females
          Produce female gametes: eggs.
        2. Testes in males
          Produce male gametes: sperm.
      4. Sexual relations play a crucial role in establishing significant bonding between a man and a woman.
        (What do you call a married couple practicing abstinence as a means of birth control? Parents.) But seriously,
      5. Procreation is a wonderful process.

    2. Female reproductive structures and processes
      16.1 Female reproductive system

      1. Structures
        1. Ovaries
          Eggs are produced in follicles. A female is born with between 30,000 and 300,000 eggs (sitting in prophase I of meiosis) in her ovaries. Ovulation is the release of an egg. In the female reproductive cyle, generally speaking, one 'month' an egg is released from one ovary and the next 'month' another is released from the other ovary.
        2. Fallopian tubes
          (Oviducts) Feather-like structures around the ovaries and the 'tubes' leading to the uterus.
        3. Uterus
          A pear-shaped structure made up of smooth muscle tissue (myometrium) and the endometrium. The myometrium is responsible for contractions.The endometrium is the vascularized (containing blood vessels) that, given that the woman is not pregnant, is sloughed off. When a female is not pregnant the uterus is 3.5" x 2.5" x 1.5". At full-term in pregnancy, the uterus is 15" x 10" x 8"--the uterus is very flexible/elastic.
        4. Cervix
          At the base of the uterus; the area that must expand to a certain size for a child to be born. When the cervix is dilated to 10
        5. Vagina
          Where the sperm is deposited. Serves as part of the birth canal.
      2. Hormone interactions relative to egg maturation
        16.2 Female Hormone Interactions
        The female cycle is about 28 days (range: 20-40 days; a lot of variation). (Day 1 is the first day of menstrual flow.) The hypothalamus (part of the brain) releases a gonadotrophin releasing hormone which is carried by the blood to the pituitary, signaling it to release FSH (follicle stimulating hormone) and LH (lutinizing hormone). These hormones are carried in the blood to the ovaries. The FSH (as named) stimulates the development of follicles (in most cases, only one matures). As the follicles begin to develop (around day 5) there is an increase in estrogen, which corresponds with an increase in the endometrium (the vascularized tissue that is sloughed off). Around the 13-14th day the estrogen reaches a peak, and there is a spike (sharp increase) in LH. Shortly after that spike, the egg is released from the follicle. This marks the end of the follicular phase and the beginning of the luteal phase. In the luteal phase, progesterone levels begins to increase. Estrogen levels dip a little but then increase as well. The follicle that has released the egg (then termed the corpus luteum) is the structure that produces the progesterone and estrogen. These hormones function to maintain and build the endometrium: this build up of blood prepares nourishment should the woman become pregnant. If fertilization occurs, these two hormones increase slightly, feeding-back to the pituitary and hypothalamus to stop the release of FSH and LH. If fertilization doesn't occur, the cycle begins anew with the sloughing off of the endometrium.
        (Review the diagram.)
      3. Female hormone patterns and their influence on puberty and sexual maturation
        1. Time frame
          Puberty: the process of reaching sexual maturity. When it begins and ends is highly variable (begins at around 10-13; ends at around 18 yrs.)
        2. Development of secondary sex characteristics
          Breast development occurs: fatty tissue deposited, axillary hair, sex organs enlarge and mature. Dr. Cates' note: a healthy amount of fat is important.
        3. Menarche
          A woman's first menstruation.
        4. Factors affecting menstrual consistency
          Diet, body weight, fatty tissue (9-10% body weight), exercise (can delay menarche/ effect menstrual consistency), disease: all can influence menstruation.
    3. Male reproductive structures and processes
      16.3 Male Reproductive System

      1. Structures
        1. Testes
          Contained within the scrotum; produce and store sperm. Contain seminiferous tubules.
        2. Duct system
          The sperm moves from the testes through the vas deferens.
        3. Auxiliary glands
          3 glands we want to talk about. The seminal vesicle adds about 60% of semen material: fructose (energy source for the sperm), prostaglandins (assist in moving sperm up female reproductive tract), etc.. The prostate gland functions to add alkaline fluids to the semen, which is important because the female tract is very acidic, and, therefore, hostile to the male sperm. The bulbourethral gland, we think, functions in adding a lubricant to the semen.
        4. It takes around 60 days for sperm to mature.

        5. Penis
      2. Sexual development in males
        1. Time frame
          Highly variable (general range: begins at 12-14, continues until 18-21 yrs.)
        2. Hormones
          The hypothalamus releases the gonadotrophin releasing hormone to the pituitary which releases the same hormones released by females: FSH and LH. The FSH in males stimulates the production of sperm. The LH is responsible for various things, including the release of testosterone. Testosterone triggers the development of secondary sex characterstics:
        3. Development of secondary sex characteristics
          An increase in skeletal muscle mass; axillary hair; deepening of voice; etc..
  2. Contraception
    1. The LDS church's policy
      from the LDS general handbook of instructions (1989):
      "Husbands must be considerate of their wives, who have a great responsibility not only for bearing children, but also for caring for them through childhood. Husbands should help their wives conserve their health and strength. Married couples should seek inspiration from the Lord in meeting their marital challenges and rearing their children according to the teachings of the gospel."
    2. Personal application